| dc.rights.license | http://creativecommons.org/licenses/by-nc/4.0 - Atribución-NoComercial | es_MX |
| dc.contributor | SAMUEL ENOCH ESTRADA SOTO | es_MX |
| dc.contributor.author | MONSERRAT HERNÁNDEZ MORALES | es_MX |
| dc.contributor.other | director - Director | es_MX |
| dc.coverage.spatial | MEX - México | es_MX |
| dc.date | 2021-03-10 | |
| dc.date.accessioned | 2022-10-25T13:27:28Z | |
| dc.date.available | 2022-10-25T13:27:28Z | |
| dc.identifier.uri | http://riaa.uaem.mx/handle/20.500.12055/2732 | |
| dc.description | Las enfermedades respiratorias representan una gran problemática a nivel
mundial, mismas que han ido en aumento debido a diferentes factores,
principalmente ambientales y genéticos. Dentro de las enfermedades respiratorias
más recurrentes se encuentran la Enfermedad Pulmonar Obstructiva Crónica
(EPOC), asma e hipertensión pulmonar. De acuerdo con los datos más recientes de
la Organización Mundial de la Salud (OMS), el asma representa una de las
principales causas de inactividad laboral e ingreso a hospitales por enfermedades
crónicas, siendo una de cada 20 personas las que padecen asma.
Si bien existen terapias farmacológica y no farmacológica para amenizar los
síntomas, los fármacos empleados no están exentos de presentar efectos adversos,
razón por la cual hay un desapego al tratamiento, aunado a esto, los costos que
representa, y algunos factores culturales. En este sentido, gran parte de la población
aun recurre a la medicina tradicional, misma que es reconocida por la OMS y por la
comunidad científica como gran reservorio de moléculas químicas con propiedades
terapéuticas y mecanismos de acción novedosos. En este sentido, Achillea
millefolium una planta medicinal utilizada en México, y de interés científico, por sus
antecedentes etnomédicos, empleada en el tratamiento de afecciones que
involucran procesos inflamatorios, como el asma. | es_MX |
| dc.description | Worldwide burden of diseases has been a health problem to worry about,
especially the diseases that affects the respiratory system and, they mainly be
caused by the environment and genetic factors, being so a focus of research. The
mainly respiratory diseases are the Chronic Obstructive Pulmonary Disease
(COPD), asthma, and pulmonary hypertension. In 2017, the World Health
Organization (WHO) reports that asthma represents one of the main causes of years
lived with disability and leading causes of burden of disease, causing the dead of
approximately 1000 people daily, affects as mainly as 339 million people, and its
prevalence is raising, hence one of every 20 people have asthma. Although asthma
has no cure, there exists a pharmacology and no-pharmacology therapy to help
patients have a better quality of life, but some patients present unwanted side
effects, and also due to long term expenses and culture, the patients tend to
abandon the pharmacologic treatment and decide to use the knowledge of the past
history and begin to treat their condition with medicinal plants, which, also the WHO
and the scientific community recognizes it as a great source of new therapeutic
agents, but in view of their uncertain efficacy, potential toxicity, the risk-benefit
relation, it ́s important to establish all the pharmacological parameters, that ́s why in
this project we decide to establish the potential activity and their mechanism of action
of the main compounds of the medicinal plant Achillea millefolium, that has been well
know and used by the population to treat different kind of pathologies that involves
an inflammatory process such as asthma. | es_MX |
| dc.format | pdf - Adobe PDF | es_MX |
| dc.language | spa - Español | es_MX |
| dc.publisher | El autor | es_MX |
| dc.rights | embargoedAccess - En Embargo | es_MX |
| dc.subject | 3 - MEDICINA Y CIENCIAS DE LA SALUD | es_MX |
| dc.subject.other | 32 - CIENCIAS MÉDICAS | es_MX |
| dc.title | Obtención de los compuestos bioactivos con potencial antiasmático a partir de Achillea millefolium | es_MX |
| dc.type | masterThesis - Tesis de maestría | es_MX |
| uaem.unidad | Facultad de Farmacia - Facultad de Farmacia | es_MX |
| uaem.programa | Maestría en Farmacia - Maestría en Farmacia | es_MX |
| dc.type.publication | acceptedVersion | es_MX |
| dc.audience | researchers - Investigadores | es_MX |
| dc.audience | 2120-01-10 | |
| dc.date.received | 2021-03-20 | |
